From Suzie: Hi everyone. The fledgling unicorn is back in the hospital. He woke up this morning with some fever and chills. This is pretty normal with CAR-T as it starts to work, the body reacts with inflammation which causes fevers. It is what is called Cytokine Release Syndrome. His case is low grade at this point and they are hoping to keep it that way by giving him an […]
It’s now D+12 and I continue to do great. No side-effect symptoms at all. We had an appointment at Stanford on Saturday for labs and vitals. Everything was normal except my sodium, so now I’m happily putting extra salt on my food per the nurse’s order. They said that Days 10 – 12 were often the times that side effects would appear, and that the other lady who got her […]
One day out of the hospital, and all is still well. Still no side effects. Suzie is diligently taking my temperature (normal) and blood pressure (ditto). Yesterday after leaving the hospital I went on a breezy, sunny 1.1 mile walk, which was pleasant and easy. I have to wear a mask outside, but just a paper N95, not the monster mask required last time I was here. Suzie did a […]
I’ve been cleared to leave the hospital tomorrow. I’m still doing great, having no side effects from the treatment. Those may arrive in the next week or so as the number of modified CAR-T cells in my bloodstream increases. If the side effects are bad enough, I might have to return to the hospital, but I’m not expecting that will happen. So I get to return to: delicious Suzie-made food, […]
I continue to have no side effects at all from my treatment. It’s quite amazing. The worst thing I’m facing is a bout of cabin fever from having to stay on the ward 24/7. Out the window I can see that it’s a beautiful evening, I can watch the wind blowing the leaves on the trees, but my room is so hermetically sealed that I might as well be viewing […]
For the first time, today I felt crummy. Not horribly bad, just run down. Operating at 80%. But that’s a good sign. It’s a sign that the infusion is doing its work, running into T-cells in my blood stream and converting them into CAR-T cells that then go and kill the myeloma cancer cells. Sometimes when I shut my eyes it’s almost as if I can feel them, or sense […]
It’s the day after I received the infusion of the KLN-1010 Phase 1 trial product. So far everything is going along as well as it could. I slept well last night (the Benedryl drowsiness won out over the dexamethasone buzz), except for being awoken at 11:30 pm and then again at 4:30 am for checks and blood draws. So far I haven’t had any symptoms from the infusion. The trial […]
After a long, not entirely restful night, today was infusion day. Originally scheduled for 9:00 am, it got delayed until 1:30, because (at the last minute, I think) the sponsor wanted a negative COVID test before the infusion could be delivered, even though I had zero systems of any respiratory problems. In the morning I got visited by various hospital personnel, including the physical therapy nurse, who administered me a […]
I’m finally starting the trial. To get updates subscribe to the site. Any new post will get sent to you automatically. Or check out that site or my new site from time to time. It’s finally here … tomorrow I get admitted to the Stanford Hospital, and the next morning I get infused with the new Phase 1 trial treatment. I’m a little freaked out about possible side effects, but […]
I got a call from Stanford yesterday confirming (finally) that I’m eligible for the Phase 1 trial. I always thought that I would be, but it wasn’t a sure thing until the trial sponsor gave final approval. I’ll be going into the hospital May 5 and getting the new treatment May 6. We finalized our rental of a place in Palo Alto so everything is set. For those interested, here’s […]